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Predoctoral Training in Drug Discovery and Experimental Therapeutics


A University-wide Interdiscipinary Program in Drug Research

Applications are invited for the Spring 2001 semester

Overview

The process of drug discovery has undergone a recent and rapid evolution. New technologies, such as Combinatorial Chemistry, have enhanced the ability of synthetic chemists to design and create large numbers of potentially active compounds. At the same time, advances in molecular biology have produced an explosion of mechanistic information on disease processes, and these suggest new points of therapeutic attack for which pharmacologically-active agents may be designed. As a result of these advances in the chemical and biological sciences, both the number and the chemical diversity of compounds available for therapeutic evaluation has created the need to develop new approaches to pharmaceutical development. In the near future, successful drug discovery programs will be those which are highly integrated in terms of the design, synthesis, and evaluation of drug candidates.

Purpose and Focus of the Program

The purpose of this predoctoral program is provide predoctoral trainees with (1) expertise training in a specific area of drug research, and (2) an awareness of the multiple scientific disciplines that are utilized in drug discovery and evaluation.

Structure of the Program

Students enrolled in this program may earn the PhD degree from a number of academic departments, including Biological Sciences, Chemistry, Neurosciences, Nuclear Medicine, Medicinal Chemistry, Pharmaceutics, Pharmacology & Toxicology, Psychology, etc. Students will choose one of these disciplines as a primary area of concentration, after exposure to diverse faculty participants in the various departments, including laboratory rotations. In addition, elective courses and an interdisciplinary approach in the thesis project will provide the desired multi-disciplinary and inter-disciplinary training. The student's dissertation project will be supervised by a major advisor within her/his discipline, in addition to input by faculty members from other disciplines. Examples of such interdisciplinary research programs within the CDDET are:
  • Biopharmaceuticals and Drug Delivery
  • Computational Aspects in Drug Discovery and Evaluation
  • Drug Synthesis, Analysis and Development
  • Mechanisms of Drug Action
  • Pharmacogenomics
  • Drug Metabolism, Pharmacokinetics and Pharmacodynamics

Training Faculty:

Over 30 faculty members are interested to be advisors of enrolled trainees. A listing is provided of these faculty, their primary department affiliations, and their research interests.

Training Environment

  • The Center for Drug Discovery and Experimental Therapeutics (CDDET) is a multi-disciplinary research center at the University at Buffalo. Many alumni of our training programs are currently employed as leaders in universities, research institutes, and the pharmaceutical industry. The program will offer a rich network for future career choices.

For More Information, send inquiries to:
Marilyn E. Morris, Ph.D.

UB WINGS CDDET HOME SEARCH

Last Modified: Tuesday 23 January, 2001